Postrepolarization Refractoriness as a Potential Anti–Atrial Fibrillation Mechanism of Pilsicainide, a Pure Sodium Channel Blocker with Slow Recovery Kinetics
- 1 January 1998
- journal article
- Published by Springer Nature in Cardiovascular Drugs and Therapy
- Vol. 12 (5) , 475-482
- https://doi.org/10.1023/a:1007758217189
Abstract
The antifibrillatory effect of pilsicainide, a sodium channel blocker with slow recovery kinetics, was investigated in a canine model of atrial fibrillation. Prolonging the atrial effective...Keywords
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