Evaluation of Cefazolin in the Treatment of Bacterial Endocarditis and Bacteremia
- 1 October 1973
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 128 (Supplement) , S392-S396
- https://doi.org/10.1093/infdis/128.supplement_2.s392
Abstract
Seven patients with bacterial endocarditis and two patients with bacteremia were treated with cefazolin, with excellent bacteriologic and good clinical response. Dosage of cefazolin was 4–12 g daily. Large doses of cefazolin (12 g/day) were tolerated well by these patients without evidence of hematotoxicity, hepatotoxicity, or nephrotoxicity. Cefazolin is an effective antimicrobial agent for treatment of serious infections caused by susceptible gram-positive organisms.Keywords
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