Unusual Cytoplasmic Body in Lymphoid Cells of Homosexual Men with Unexplained Lymphadenopathy

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Abstract
Unexplained chronic generalized lymphadenopathy has recently been reported in homosexual men in several metropolitan areas in the United States.1 Lymph-node biopsies from these patients have shown reactive lymphoid hyperplasia by light microscopy. Concurrently, there have been reports of a new acquired immune-deficiency syndrome (AIDS) manifested by neoplasms and opportunistic infections; this condition has appeared in the same time period, geographic locations, and population groups as the unexplained lymphadenopathy.2 3 4 5 Lymphadenopathy may represent an early stage of AIDS, since it has preceded this syndrome in many cases.5 , 6 Early diagnosis, treatment, and prevention of AIDS have been seriously hampered by the lack of . . .

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