The sensitizing potency of Euxyl® K 400 and its components 1,2‐dibromo‐2,4‐dicyanobutane and 2‐phenoxyethanol

Publisher Website
Google Scholar
Abstract
Using a modified FCA (Freund's complete adjuvant) procedure, the sensitizing capacity of Euxyl K® 400 and its ingredients, 1,2‐dibromo‐2.4‐dicyanobutane and 2‐phenoxyethanol, has been studied in guinea pigs. The experiments demonstrate that a distinct but weak sensitizing potency exists for Euxyl® K 400 and dibromodicyanobutane. Phenoxyethanol remained almost negative. These results are in good accordance with the low number of cases of allergic contact dermatitis due to Euxyl® K 400 and dibromodicyanobutane described since their introduction on the market. Cases of phenoxyethanol contact allergy have been published hitherto only 4× in the medical literature.