Pulmonary embolism and transitory anti-b2-GPI antibodies in an adult with chicken pox
- 1 September 2000
- journal article
- research article
- Published by SAGE Publications in Lupus
- Vol. 9 (7) , 558-560
- https://doi.org/10.1177/096120330000900716
Abstract
Anti-β2-glycoprotein I antibodies are considered as a specific marker for the antiphospholipid syndrome. In contrast to lupus circulating anticoagulant and anticardiolipin (aCL) antibodies, they are usually not found at significant levels in infections. We report a case of pulmonary embolism in an adult with varicella. Transient significant levels of aCL antibodies and of IgM anti-b2-GPI antibodies were observed. No other prothrombotic factor, including free protein S antigen deficiency, was found. The direct pathogenic role of these transient antibodies on the thrombotic event may then be suspected. They are probably associated with VZV acute infection and are absent two months after varicella.Keywords
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