The role of pancreatic exocrine secretions in the absorption of vitamin B12 and iron

Abstract
Pancreatic dysfunction is associated with decreased absorption of B12 and increased absorption of iron. The decreased B12 absorption is reproducibly improved by oral therapy with pancreatic exocrine secretions (pancreatin or bicarbonate, or both); increased iron absorption is not as reproducibly improved by such oral therapy. The specific roles of pancreatic exocrine secretions in absorption of B12 and iron await greater elucidation by further research.
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