RNase T1 mutant Glu46Gln binds the inhibitors 2′GMP and 2′AMP at the 3′ subsite
- 1 May 1992
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 225 (2) , 533-542
- https://doi.org/10.1016/0022-2836(92)90937-f
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Synthesis and kinetic study of transition state analogs for ribonuclease T1Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1991
- Crystal structure of ribonuclease T1 complexed with adenosine 2'-monophosphate at 1.8-A resolutionPublished by Elsevier ,1991
- Studies on RNase T1 mutants affecting enzyme catalysisEuropean Journal of Biochemistry, 1991
- Relative binding free energy calculations of inhibitors to two mutants (Glu46— Ala/Gln) of ribonuclease T1 using molecular dynamics/free energy perturbation approachesProtein Engineering, Design and Selection, 1991
- Calculation of the relative binding free energy of 2′GMP and 2′AMP to ribonuclease T1 using molecular dynamics/free energy perturbation approachesJournal of Molecular Biology, 1990
- Specific protein-nucleic acid recognition in ribonuclease T1–2′-guanylic acid complex: an X-ray studyNature, 1982
- Crystallization of a Complex between Ribonuclease T1 and 2'-Guanylic AcidEuropean Journal of Biochemistry, 1980
- Proton magnetic resonance studies of ribonuclease T1 Assignment of histidine‐27 C2‐H and C5‐H proton resonances by a photooxidation reactionFEBS Letters, 1978
- Conformational analysis of the sugar ring in nucleosides and nucleotides. New description using the concept of pseudorotationJournal of the American Chemical Society, 1972
- Binding of purine nucleoside monophosphates by ribonuclease T1 a model system for protein nucleic acid interactionBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971