Effect of Diisopropylfluorophosphate on Sulfhydryl Proteases
- 19 June 1959
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 129 (3364) , 1678
- https://doi.org/10.1126/science.129.3364.1678
Abstract
Diisopropylfluorophosphate inhibited all the sulfhydryl proteases studied in our tests. This inhibition was most pronounced at pH 6.0. By first blocking the sulfhydryl group with p-chloromercuribenzoate, inhibition could be prevented. Neither cysteine nor choline gave appreciable reactivation of diisopropylfluorophosphate-inhibited bromelain.Keywords
This publication has 2 references indexed in Scilit:
- THE INHIBITION OF PLASMIN BY TOXIC PHOSPHORUS COMPOUNDSJournal of Biological Chemistry, 1958
- The inhibition of thrombin by diisopropyl phosphorofluoridateArchives of Biochemistry and Biophysics, 1956