The effect of indomethacin and enalapril on the cutaneous response to bradykinin.
- 1 June 1989
- journal article
- research article
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 27 (6) , 870-872
- https://doi.org/10.1111/j.1365-2125.1989.tb03452.x
Abstract
The angiotensin converting enzyme inhibitors potentiate the wheal response to intradermal bradykinin. Both converting enzyme inhibitors and bradykinin stimulate prostaglandin synthesis and prostaglandins enhance the cutaneous response to bradykinin. We examined the possibility that the increased wheal response to intradermal bradykinin in the presence of enalapril was due to the effect of prostaglandins. Indomethacin did not inhibit the potentiation by enalapril of the wheal response to bradykinin.This publication has 13 references indexed in Scilit:
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