Chemical Studies on Tobacco Smoke LXVII. Quantitative Determination of Alkaloids in Tobacco by Liquid Chromatography
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 3 (10) , 1505-1515
- https://doi.org/10.1080/01483918008062792
Abstract
An HPLC method was developed for the quantitative determination of individual alkaloids of the basic fraction of tobacco extracts. Two reverse phase RP-18 columns were used, eluting with a gradient of aqueous triethylamine phosphate buffer (pH 7.56) and acetonitrile. The method was optimized and compared favorably with existing quantitative techniques in regard to time factors, sensitivity and accuracy.This publication has 7 references indexed in Scilit:
- CHEMICAL STUDIES ON TOBACCO-SMOKE .62. ASSESSMENT OF TOBACCO-SPECIFIC N-NITROSAMINES IN TOBACCO PRODUCTS1979
- Chemical studies on tobacco smoke XXIII. Synthesis of carbon‐14 labelled myosmine, nornicotine and N′‐nitrosonornicotineJournal of Labelled Compounds and Radiopharmaceuticals, 1974
- 1′-Hexanoylnornicotine and 1′-octanoylnornicotine from tobaccoPhytochemistry, 1972
- The Synthesis of Anatabine and Related Compounds1The Journal of Organic Chemistry, 1965
- COMPARISON OF PHARMACOLOGICAL ACTIVITY OF NICOTINE AND RELATED ALKALOIDS OCCURRING IN CIGARETTE SMOKE1965
- Tertiary Amine Oxide Rearrangements. III. The Mechanism of the Demethylation of NicotineJournal of the American Chemical Society, 1964
- Demethylation of Cotinine in Vivo1Journal of the American Chemical Society, 1959