Oguchi's Disease

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Abstract
Introduction In 1907 Oguchi1 described a form of night blindness associated with a diffuse greyish discoloration of the fundus. Over the next 20 years more than 60 cases were observed, all by Japanese authors. In 1927 Scheerer2 reported the first European cases and since then, 24 patients with this disease have been reported on the continent. Klien,3 in 1939, discussed the first case seen in the United States, and follow-up reports on this patient were subsequently made by Wilder4 and Krill.5 The features which differentiate most cases of this type of nyctalopia from other disorders of congenital stationary night blindness are the appearance of the fundus and the fact that prolonged dark adaptation will lead to a disappearance of the abnormal fundus coloration and normalization of all psychophysical testing parameters. Of note also is the peculiar histologic picture. The presence of an abnormally large number