Protiodeacetylation of porphyrins and pyrroles: a new partial synthesis of dehydrocoproporphyrin (S411-porphyrin)

Abstract
Treatment of copper(II) complexes of acetyl-porphyrins with ethanedithiol and boron trifluoride–ether in acetic acid efficiently accomplishes deacetylation of the porphyrin system, and this reaction is demonstrated in a new partial synthesis of dehydrocoproporphyrin (S411-porphyrin); acetylpyrroles are also quantitatively deacetylated under these conditions.

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