Transient neonatal diabetes and later onset diabetes: a case of inherited insulin resistance.
- 1 January 1995
- journal article
- case report
- Published by BMJ in Archives of Disease in Childhood
- Vol. 72 (1) , 56-57
- https://doi.org/10.1136/adc.72.1.56
Abstract
A 13 year old girl who had had transient neonatal diabetes developed permanent diabetes. She had raised fasting insulin concentrations suggestive of insulin resistance with a suboptimal insulin response to glucose loading. Both her mother and sister had profound insulin resistance; neither had clinical diabetes. This is the first time inherited insulin resistance has been implicated in the pathogenesis of permanent diabetes developing after transient neonatal diabetes.Keywords
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