Separation of DNA Fragments by High-Performance Liquid Chromatography and Capillary Electrophoresis

Abstract
High resolution separations of DNA fragments up to 10,000 base pairs have been performed using high-performance liquid chromatography, capillary gel electrophoresis, and capillary electrophoresis in entangled polymer solutions. These methods were compared with respect to their performance and efficiencies in the resolution of DNA fragments.