Monitoring and evaluation of programmes to prevent mother to child transmission of HIV in Africa
- 31 May 2007
- Vol. 334 (7604) , 1143-1146
- https://doi.org/10.1136/bmj.39211.527488.94
Abstract
Strategy to prevent transmissionEstimates of the efficacy of antiretroviral prophylaxis3 suggest that at least half of the world's children who are at risk of HIV infection might be protected if a mother receives antenatal care, is offered HIV counselling and testing, and, if infected, she and her baby receive prophylaxis. Prophylaxis is the mainstay of the strategy to prevent mother to child transmission.3 Several antiretroviral regimens are recommended in resource constrained settings, although nevirapine (either alone or with other drugs) is usually favoured because it is cheap, easy to administer, rapidly absorbed, and has a long half life.3 Depending on the regimen and the mother's choice of infant feeding, the risk of HIV transmission can be reduced to <2%.3 Whenever feasible, programmes should strive to provide highly active antiretroviral therapy to pregnant women. Although formula feeding can reduce HIV infection rates among infants,4 it is often not acceptable, feasible, affordable, sustainable, or safe in resource limited settings.5 6 Programmes should provide counselling and support on various feeding options (including exclusive breastfeeding), highlighting the potential benefits and risks of each.7 Other activities include promotion of optimal obstetrical practices; improvement of antenatal, postnatal, and child health services; and treatment of maternal diseases. Community based activities are also often implemented to improve community knowledge of HIV and AIDS and counter negative attitudes to people with HIV.8Keywords
This publication has 18 references indexed in Scilit:
- High acceptability of voluntary counselling and HIV‐testing but unacceptable loss to follow up in a prevention of mother‐to‐child HIV transmission programme in rural Malawi: scaling‐up requires a different way of actingTropical Medicine & International Health, 2005
- Preventing Mother-to-Child Transmission of HIV in Western KenyaJAIDS Journal of Acquired Immune Deficiency Syndromes, 2005
- Health system constraints to optimal coverage of the prevention of mother-to-child HIV transmission programme in South Africa: lessons from the implementation of the national pilot programme.African Health Sciences, 2005
- Effectiveness of a city-wide program to prevent mother-to-child HIV transmission in Lusaka, ZambiaAIDS, 2005
- Effectiveness of the first district-wide programme for the prevention of mother-to-child transmission of HIV in South Africa.2005
- An electronic medical record system for ambulatory care of HIV-infected patients in KenyaInternational Journal of Medical Informatics, 2005
- Preventing HIV transmission to children: Quality of counselling of mothers in South AfricaActa Paediatrica, 2005
- Prevention of mother to child transmission of HIV: evaluation of a pilot programme in a district hospital in rural ZimbabweBMJ, 2004
- Preventing Mother-to-Child HIV Transmission in a Developing CountryJAIDS Journal of Acquired Immune Deficiency Syndromes, 2003
- Low Rate of Mother-to-Child Transmission of HIV-1 After Nevirapine Intervention in a Pilot Public Health Program in Yaound??, CameroonJAIDS Journal of Acquired Immune Deficiency Syndromes, 2003