Intraepithelial lymphocytes in the jejunal mucosa of malnourished rats.
Open Access
- 1 January 1980
- Vol. 21 (1) , 32-36
- https://doi.org/10.1136/gut.21.1.32
Abstract
Intraepithelial lymphocytes (IEL) have been counted in the jejunal mucosa of adult Wistar rats submitted to a protein-free diet for 84 days and of a control group receiving a 20% casein diet, in order to evaluate the effect of protein deprivation. Relative counts (IEL/100 epithelial cells), absolute counts (number of IEL per millimetre of muscularis mucosae), and the proportion of lymphocytes crossing the basement membrane have been evaluated. Both relative and absolute IEL counts were diminished but the proportion of crossing lymphocytes was greatly increased in the malnourished group. The low number of IEL seemed to be related to lymphatic vessel dilatation in the lamina propria. The possibly primary effect of malnutrition on IEL counts in our experimental model and the eventual role of the observed lymphatic dilatation have been discussed.This publication has 17 references indexed in Scilit:
- Intraepithelial lymphocytes of the small intestine.Gut, 1977
- Evaluation of the intraepithelial lymphocyte count in the jejunum in childhood enteropathies.Gut, 1976
- INTRAEPITHELIAL LYMPHOCYTE COUNTS IN SMALL INTESTINAL BIOPSIES FROM CHILDREN WITH DIARRHOEAActa Paediatrica, 1976
- Cellular infiltrate of the jejunum after re-introduction of dietary gluten in children with treated coeliac disease.Journal of Clinical Pathology, 1976
- The cellular infiltrate of the jejunum in adult coeliac disease and dermatitis herpetiformis following the reintroduction of dietary gluten.Gut, 1975
- Letter: Intra-epithelial lymphocytes in the jejunum of malnourished children.1974
- The cell population of the upper jejunal mucosa in tropical sprue and postinfective malabsorptionGut, 1974
- Factors Affecting the Lymphoid Cells in the Small Intestinal Epithelium of the MouseInternational Archives of Allergy and Immunology, 1973
- Quantitation of intraepithelial lymphocytes in human jejunumGut, 1971
- Electron and light microscopic observations on relationships between lymphocytes and intestinal epitheliumJournal of Anatomy, 1967