The tor pathway: a target for cancer therapy
Top Cited Papers
- 1 May 2004
- journal article
- review article
- Published by Springer Nature in Nature Reviews Cancer
- Vol. 4 (5) , 335-348
- https://doi.org/10.1038/nrc1362
Abstract
No abstract availableKeywords
This publication has 166 references indexed in Scilit:
- Rheb is a direct target of the tuberous sclerosis tumour suppressor proteinsNature Cell Biology, 2003
- Rheb is an essential regulator of S6K in controlling cell growth in DrosophilaNature Cell Biology, 2003
- TOR signalling in bugs, brain and brawnNature Reviews Molecular Cell Biology, 2003
- mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth MachineryCell, 2002
- Myogenic Differentiation Is Dependent on Both the Kinase Function and the N-terminal Sequence of Mammalian Target of RapamycinPublished by Elsevier ,2002
- 4E-binding Proteins, the Suppressors of Eukaryotic Initiation Factor 4E, Are Down-regulated in Cells with Acquired or Intrinsic Resistance to RapamycinJournal of Biological Chemistry, 2002
- Regulation of cell size in growth, development and human disease: PI3K, PKB and S6KBioEssays, 2002
- The Mammalian Target of Rapamycin Regulates C2C12 Myogenesis via a Kinase-independent MechanismJournal of Biological Chemistry, 2001
- Coexpression of hepatocyte growth factor-Met: an early step in ovarian carcinogenesis?Oncogene, 2001
- Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle.The Journal of Antibiotics, 1975