Tumor-associated tissue eosinophilia in nasopharyngeal carcinoma. A pathologic study of 422 primary and 138 metastatic tumors
- 1 February 1987
- Vol. 59 (3) , 466-470
- https://doi.org/10.1002/1097-0142(19870201)59:3<466::aid-cncr2820590319>3.0.co;2-p
Abstract
A study of biopsy specimens from 422 consecutive primary nasopharyngeal carcinomas (NPCs) revealed tumor-associated tissue eosinophilia (TATE) in a large proportion (26%) of the tumors. TATE occurred more frequently in nonkeratinizing carcinomas (NKC, 38%) than in the squamous (21%) or undifferentiated (23%) types. There was no sex predilection and no association with the presence of intratumor amyloid deposits. Stromal eosinophilia was also observed in 53 (38%) of 138 metastatic NPCs in lymph nodes, where it had occasionally led to confusion with Hodgkin's disease. TATE may be a feature of diagnostic importance in NPC, although its prognostic significance remains to be ascertained.This publication has 20 references indexed in Scilit:
- Eosinophil infiltration in keratoacanthoma and squamous cell carcinoma of the skinHistopathology, 1984
- Tumour-associated eosinophilia in the bladder.Journal of Clinical Pathology, 1984
- Localized amyloidosis in nasopharyngeal carcinomaHistopathology, 1984
- Cervical carcinoma and eosinophilClinical Immunology and Immunopathology, 1981
- Tumour-associated eosinophilia: a review.Journal of Clinical Pathology, 1981
- Bronchial carcinoma with eosinophilia and cardiomegalyRespiratory Medicine, 1975
- Eosinophil chemotaxis of supernatants from cultured Hodgkin's lymph node cells.Journal of Clinical Pathology, 1975
- Formation of eosinophilic‐like granulocytic colonies by mouse bone marrow cells in vitroJournal of Cellular Physiology, 1974
- Tumor-Associated Eosinophilotactic FactorNew England Journal of Medicine, 1974
- The eosinophil and gastrointestinal carcinomaThe American Journal of Surgery, 1959