Transfer with RNA Extracts of the Cell Migration Inhibition Correlate of Delayed Hypersensitivity in the Guinea Pig

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Abstract
Summary: When guinea pig nonsensitive peritoneal exudate cells were incubated with RNA extracts obtained from the lymph nodes and spleens of guinea pigs sensitive to PPD or coccidioidin, the migration of these cells from capillary tubes was specifically inhibited by the antigen to which the RNA donor was sensitive. Neither the antigen alone nor RNA extracts from unimmunized guinea pigs were able to convert these cells to a state of sensitivity.

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