Synthesis of the untriacontapeptide corresponding to the entire amino acid sequence of human .BETA.-endorphin.

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Abstract
In a conventional manner, the untriacontapeptide corresponding to the entire amino acid sequence of human β-endorphin was synthesized using amino acid derivatives, Lys (Z) Glu (OBzl), bearing protecting groups removable by methanesulfonic acid. Potency ratios of the synthetic peptide to morphin (taken as 1) was 6.5, when assayed the analgesic effect on tail pinch method in mice.

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