Consequences of Total and Subtotal Myeloperoxidase Deficiency: Risk or Benefit ?
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- 1 November 2000
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 104 (1) , 10-15
- https://doi.org/10.1159/000041062
Abstract
A group of 100 totally or subtotally myeloperoxidase (MPO)-deficient individuals was compared to a reference population of 118 probands selected at random. Data for a protective effect of the deficiency against cardiovascular damage are presented. On the other hand, a significantly higher occurrence of severe infections and chronic inflammatory processes was noted among the deficient patients. An increased incidence of cancer among the MPO-deficient individuals was not demonstrated.Keywords
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