Abstract
In a sample of 12,030 subjects, ranging in age from 8 to 99 years, significant decreases in both mixed and consistent left-handedness were found as age increased. There were also significant sex differences, with males more likely to be left- or mixed-handed. These age and sex differences were reported as non-significant in Porac's (1993) smaller sample of 654. Methodological issues associated with asserting the null hypothesis in handedness studies when statistical power is low are also discussed.

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