BRAIN GLYCOPROTEIN IN TUMOURS OF THE NERVOUS SYSTEM
- 1 January 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Neuropathology and Experimental Neurology
- Vol. 39 (1) , 88-98
- https://doi.org/10.1097/00005072-198001000-00008
Abstract
We studied various tumours of the nervous system by the immunofluorescence technique using an anti-brain specific alpha 2 glycoprotein antiserum (anti-NSA3 antiserum). We found the antigen in 24/27 astrocytomas and 4/4 oligodendrogliomas but in none of the 8 meningiomas tested. There was an identity between the astrocytoma/oligodendroglioma antigen and that of normal brain as shown by the immunoprecipitation technique. By the immuno-fluorescence technique using inhibition of the antiserum we demonstrated that the tumour antigen is devoid of some specific nervous system determinants present in normal brain.This publication has 2 references indexed in Scilit:
- Glial fibrillary acidic protein in tumours of the nervous systemBritish Journal of Cancer, 1978
- THE VALUE OF LDH ISOENZYMES IN THE RAPID DIAGNOSIS OF BRAIN TUMOURSNeuropathology and Applied Neurobiology, 1976