Prediction of Sentinel Lymph Node Micrometastasis by Histological Features in Primary Cutaneous Malignant Melanoma

Abstract
APPROPRIATE treatment and counseling of patients with malignant melanoma depends on an understanding of the individual patient's prognosis. The prognosis of primary cutaneous clinical stage I malignant melanoma has been shown to correlate most closely with vertical thickness of the primary tumor.1 Anatomical location and patient sex are 2 other modifying factors that consistently appear to influence prognosis.1-7 Age of the patient and pathological features, such as ulceration, microsatellitosis, lymphatic invasion, and extensive regression, may likewise adversely affect prognosis.1-7

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