Immunological agnosis: a state that derives from T suppressor cell inhibition of antigen-presenting cells.

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Abstract
The biologically active mediators of antigen-specific mouse T suppressor cells can combine with antigen on cells that are specialized to present antigen (APC) and render these APC incapable of presenting not only the specific antigen that the product of the T suppressor cells sees but also any other antigen in or on the APC. Antigen-bearing suppressed APC failed to activate either the helper or suppressor systems involved in the regulation of contact sensitivity responses. APC are targets of T suppressor cells. A metabolic event is required for functional antigen presentation and T suppressor cells can block that metabolic pathway.