Brain Abscess Caused byCladosporium Trichoides: Review of 3 Cases and Report of Fourth Case

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Abstract
The 3 previous cases of mycotic brain abscess caused by Cladosporum trichoides are reviewed and a fourth case is reported. Two of the patients were from Louisiana, including the one described in this paper. The portal of entry has not been established in any of the cases, but 2 of the patients had ear infections. The presently recognized clinical factors in all of the Cases are referable to the central nervous system, i.e., headache, lethargy, convulsions, and hemiparesis, and there is a conspicuous absence of systemic features. Encephalograms provided the means of locating a space-occupying lesion in all 4 patients. This fungus seems to have an affinity for brain tissue. Examination of specimens removed at surgery, and at autopsy revealed that no definite capsule could be identical at the periphery of the abscesses. Brown septate hyphae were present in giant cells and in other parts of the lesion.

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