Amplification of the met gene in glioma
- 1 January 1995
- journal article
- research article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 12 (1) , 63-65
- https://doi.org/10.1002/gcc.2870120111
Abstract
We have previously reported the finding of MET amplification linked to double minutes (dmins) in a human glioblastoma (TX3095). Because dmins are found in approximately 50% of glioblastomas, 18 gliomas were analyzed for MET amplification. Three grade IV glioblastomas and one grade II astrocytoma showed amplification. We could also localize the MET amplicon to dmins in glioblastoma TX3095 by fluorescence in situ hybridization.Keywords
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