[The epidemiology of Wilson's disease in the German Democratic Republic and current problems from the viewpoint of population genetics].

  • 1 July 1979
    • journal article
    • abstracts
    • Vol. 31  (7) , 393-400
Abstract
Between 1949 and Nov. 30, 1977 a total of 123 cases of Wilson's disease have been registered in the GDR. Using the available statistics the incidence rate of the disease is assumed to be about 2.9/100,000, the gene frequency approx. 0.53 per cent and the heterozygote incidence 1.05 per cent, supposing that the Hardy-Weinberg law applies to a large extent. Conclusions are drawn from the available material with a view to detection of the disease infuture and to genetic family counselling.

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