Studies on Dracunculus medinensis (Linnaeus) II. Effect of Acidity on the Infective Larva

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Abstract
Infective third-stage larvae of Dracunculus medinensis in cyclops have been maintained at 37°C in normal saline containing from 0·05 to 1·0% of hydrochloric acid. At acid levels normally met with in the human stomach 50% mortality of emerging larvae occurred in 150 minutes, suggesting that the time taken for larvae to pass through the stomach may be of importance in determining whether an infection is successful or not.