Single-Step Synthesis of Racemic Di- and Tripeptides Derived from Unnatural β-Hydroxy and β-Mercapto α-Amino, Acids by the Ugi Reaction
- 1 January 1994
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1994 (06) , 619-623
- https://doi.org/10.1055/s-1994-25535
Abstract
An efficient single-step selective synthesis of oligopeptide analogues, which contain amino acid analogues and are derivatives of 3-thiazolidines and 3-oxazolidine, through the use of hydrochloric acid as the protecting agent is described. These compounds are prepared based on the Ugi four component condensation (4CC) reaction.Keywords
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