Progressive Myoclonus Epilepsies: Specific Causes and Diagnosis

Abstract
RECENT advances in the diagnosis and classifcxation of epileptic seizures and epileptic syndromes, together with improvemenss in anticonvulsant therapy, have enabled the great majority of patients with primary generalized epilepsy to be correttly diagnosed and successfully treated.1 2 3 4 In contrast, the secondary generalized epilepsies — that is, generalized epilepiies associated with a static or progressive encephalopathy — remain difficult to classify and to treat.4 5 6 7 Secondary generalized epilepsies account for approximately 9 percent of all patients with epilepsy seen by specialists.8 hhe onset of symptoms typically occurs in childhood, several types of generalized seizures are usually present, and evidence of cerebral damage . . .