HLA Antigens in Diabetic Children

1 September 1977

journal article
research article
Published by American Diabetes Association in Diabetes

Vol. 26 (9) , 870-873
https://doi.org/10.2337/diab.26.9.870

Abstract

Ninety insulin-dependent diabetic children were HLA-typed in order to elucidate the role played by HLA complex-linked genes in the pathogenesis of diabetes melHtus of childhood. HLA-Aw30 and HLA-Bw35 were significantly increased and decreased, respectively, in the diabetic group as compared with controls. In relation to age at onset of diabetes, HLA-B8 was significantly increased in the 0-5-year group. By dividing the patients according to the season at onset of the disease, only HLA-Aw30 in the October-January group reached the level of significance (P=0.05).

This publication has 3 references indexed in Scilit:

HL-A IN GRAVES-DISEASE AND IN DIABETES-MELLITUS INSULIN-DEPENDENT
1975
Genetics of Diabetes Mellitus
Diabetes, 1967
ON ESTIMATING THE RELATION BETWEEN BLOOD GROUP AND DISEASE
Annals of Human Genetics, 1955