Limitations of Metabolic Activation Systems Used with in Vitro Tests for Carcinogens
- 25 July 1980
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 209 (4455) , 503-505
- https://doi.org/10.1126/science.6771871
Abstract
Important differences between the metabolic activation of 7,12-dimethylbenz[a]anthracene in intact cellular systems and in liver homogenates suggest that the use of homogenates in conjunction with short-term assays for carcinogens could yield misleading results.Keywords
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