THE ETIOLOGY OF THE TYPHUS FEVER (TABARDILLO) OF MEXICO CITY

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Abstract
Some months ago1we reported an experiment in which the virus of typhus, as it exists in the diluted serum of the patient, failed to pass through a Berkefeld filter. The monkey which received the unfiltered serum, exhibited a severe course of fever after an incubation period of five days, whereas the animal which received the filtered serum developed no fever and remained perfectly well. The immunity test, which has not been reported heretofore, confirmed the conclusion that the virus did not pass through the filter. This test, which was given about one month following the "filtration experiment," consisted of the intraperitoneal injection of 7 c.c. of diluted defibrinated blood drawn from a human patient on the tenth or eleventh day of his fever. No. 3, which had tolerated the filtered serum without visible disturbance, showed a course of high fever lasting eleven days, and preceded by an incubation period

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