Nucleolus degradation and growth induced by uv-microbeam irradiation of interphase cells grown in culture.

Open Access
Publisher Website
Google Scholar
Abstract
In contrast to total cell irradiation, local UV-microbeam irradiation can stimulate a significant diminution in the irradiated mature nucleoli in interphase pig embryo cells in culture. This diminution is accompanied by the concomitant expansion of the unirradiated nucleoli within the same nucleus, and the total nucleolar volume per nucleus does not change appreciably. These nucleolar volume changes may be the result of the dispersion, migration and redistribution of the nucleolar material between competitive nucleolar organizer regions of the interphase nucleus.