Measurement of Central Venous Oxygen Saturation in Patients with Myocardial Infarction

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Abstract
Central venous oxygen saturation (CVSO2) was measured in 31 patients with myocardial infarction. CVSO2 correlated well with the patients' clinical course. In those patients not in heart failure, mean ± sem for CVSO2 was 70 ± 1%. When heart failure was present, CVSO2 averaged 56 ± 1%. When both heart failure and shock were present, CVSO2 averaged 43 ± 1%. In nine patients, serial determinations of arterial oxygen saturation and CVSO2 were made. In 22 of 26 instances, either a fall in CVSO2 was accompanied by an increase in the arteriovenous oxygen saturation difference or an increase in CVSO2 was accompanied by a decrease in arteriovenous oxygen saturation difference. Serial measurements of CVSO2 appear to be a useful method of monitoring changes in myocardial function in patients with myocardial infarction.

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