Predominant transesterification reaction catalyzed by immobilized trypsin.

Abstract
Immobilized trypsin covalently attached to cross-linked dextran was prepared. In the presence of high concentrations of primary and secondary alcohols, the transesterification of L-lysine esters catalyzed by the immobilized trypsin was observed to be predominant. No transesterified product was detected with tertiary butyl alcohol. These reactions were compared with the acid-catalyzed transesterification reactions and the characteristics of the enzymatic reaction are discussed.

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