Clinical Management of Filovirus-Infected Patients
Open Access
- 20 September 2012
- Vol. 4 (9) , 1668-1686
- https://doi.org/10.3390/v4091668
Abstract
Filovirus infection presents many unique challenges to patient management. Currently no approved treatments are available, and the recommendations for supportive care are not evidence based. The austere clinical settings in which patients often present and the sporadic and at times explosive nature of filovirus outbreaks have effectively limited the information available to evaluate potential management strategies. This review will summarize the management approaches used in filovirus outbreaks and provide recommendations for collecting the information necessary for evaluating and potentially improving patient outcomes in the future.Keywords
This publication has 94 references indexed in Scilit:
- Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learnedBMC Infectious Diseases, 2011
- Outbreak of Marburg Hemorrhagic Fever Among Miners in Kamwenge and Ibanda Districts, Uganda, 2007The Journal of Infectious Diseases, 2011
- Emergence of Divergent Zaire Ebola Virus Strains in Democratic Republic of the Congo in 2007 and 2008The Journal of Infectious Diseases, 2011
- Clinical Aspects of Marburg Hemorrhagic FeverFuture Virology, 2011
- Availability of critical care resources to treat patients with severe sepsis or septic shock in Africa: a self-reported, continent-wide survey of anaesthesia providersCritical Care, 2011
- Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviationsArchiv für die gesamte Virusforschung, 2010
- Reducing mortality in severe sepsis with the implementation of a core 6-hour bundle: results from the Portuguese community-acquired sepsis study (SACiUCI study)Critical Care, 2010
- The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsisIntensive Care Medicine, 2010
- Severe Sepsis in Two Ugandan Hospitals: a Prospective Observational Study of Management and Outcomes in a Predominantly HIV-1 Infected PopulationPLOS ONE, 2009
- Outbreake of Marburg virus disease in Johannesburg.BMJ, 1975