Anaphylactic Drug Reactions

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Abstract
The efficacy of new drugs has often been offset by their ability to sensitize the patient. The allergic reactions that result later on when the drug is used again are encountered in every field of medicine. The frequency of unfavorable reactions can be reduced by avoiding unnecessary medication, by using parenteral and topical methods of administration only when necessary, by knowing the allergenic potentialities of the given drug, and by ascertaining the patient's history with respect to allergies. Tests for drug sensitivity are of limited value, and the author advises against the prophylactic use of antihistaminics in the same syringe with an antibiotic. When it is necessary to administer a drug parenterally, the equipment needed in dealing with emergencies should be at hand.

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