Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
- 1 January 2001
- journal article
- Published by Elsevier in Medical Hypotheses
- Vol. 56 (1) , 8-11
- https://doi.org/10.1054/mehy.1999.1015
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Zonated expression of cytokines in rat liver: Effect of chronic ethanol and the cytochrome P450 2E1 inhibitor, chlormethiazoleHepatology, 1998
- Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humansHepatology, 1997
- Cytochrome P-4502E1: its physiological and pathological rolePhysiological Reviews, 1997
- Ethanol metabolism, cirrhosis and alcoholismClinica Chimica Acta; International Journal of Clinical Chemistry, 1997
- Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers*Clinical Pharmacology & Therapeutics, 1996
- Suppression of rat hepatic cytochrome P450 2E1 expression by isopropyl 2-(1,3-dithioetane-2-ylidene)-2-[N-(4-methyl-thiazol-2-yl)carbamoyl]acetate (YH439), an experimental hepatoprotectant: Protective role against hepatic injuryBiochemical Pharmacology, 1996
- Effects of cytochrome p450 2E1 modulators on the pharmacokinetics of chlorzoxazone and 6-hydroxychlorzoxazone in ratsLife Sciences, 1996
- Transcriptional Inhibition of Cytochrome P4502E1 by a Synthetic Compound, YH439Archives of Biochemistry and Biophysics, 1996
- Evidence that Cytochrome P‐4502E1 Contributes to Ethanol Elimination at Low Doses: Effects of Diallyl Sulfide and 4‐Methyl Pyrazole on Ethanol Elimination in the Perfused Rat LiverAlcohol, Clinical and Experimental Research, 1996
- Ethanol-inducible cytochrome P4502E1: Genetic polymorphism, regulation, and possible role in the etiology of alcohol-induced liver diseaseAlcohol, 1993