Model for the Molecular Genetic Diagnosis of Endometrial Cancer Using K-ras Mutation Analysis
Open Access
- 1 April 1998
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 90 (7) , 540-542
- https://doi.org/10.1093/jnci/90.7.540
Abstract
Endometrial cancer is the most common female genital tract cancer in Western societies (1). The prognosis for endometrial cancer is closely associated with tumor stage and histology (2). Currently, almost all cases are diagnosed following presentation with postmenopausal bleeding. Although the value of screening women in the general population for endometrial cancer is questionable, there are arguments for screening selected populations, such as women who belong to cancer-susceptible families [e.g., those with the Lynch II cancer family syndrome (3)] and women who are taking tamoxifen (4).Keywords
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