Fish myosin alkali light chains originate from two different genes
- 1 August 1991
- journal article
- Published by Springer Nature in Journal of Muscle Research and Cell Motility
- Vol. 12 (4) , 366-371
- https://doi.org/10.1007/bf01738591
Abstract
We have determined the amino acid sequences of mullet white skeletal muscle myosin alkali light chains, LC1 and LC3. These are the first available fish myosin sequences. There are 29 differences between the mullet LC1 and LC3 sequences, spread throughout all regions of their polypeptide chains, leading us to conclude that fish myosin alkali light chains originate from two different genes. This finding is in sharp contrast to all previous studies on vertebrate fast skeletal muscle myosins, which showed that in birds and mammals LC1 and LC3 are produced from a single gene by alternative RNA transcription and splicing, yielding proteins which differ only in their N-terminal segments.Keywords
This publication has 26 references indexed in Scilit:
- Myosin light chains and troponin C: Structural and evolutionary relationships revealed by amino acid sequence comparisonsJournal of Muscle Research and Cell Motility, 1991
- The amino acid sequence of ascidian (Halocynthia roretzi) myosin light chainsBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986
- Amino acid sequence of myosin essential light chain from the scallop Aquipecten irradiansBiochemistry, 1986
- The light chains of muscle myosin: Its structure, function, and evolutionAdvances in Biophysics, 1983
- Identification of 5,5'-dithio-bis-2-nitrobenzoic acid (DTNB) and alkali light chains of piscine myosin.NIPPON SUISAN GAKKAISHI, 1982
- Distribution of light chains in fast skeletal myosinNature, 1979
- Isolation and characterization of the three light chains from carp white muscle myosinArchives Internationales de Physiologie et de Biochimie, 1977
- Light Chains from Fast and Slow Muscle MyosinsNature, 1971
- Substructure of the myosin moleculeJournal of Molecular Biology, 1971
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970