Pyrroles and related compounds. Part XXV. Pemptoporphyrin, isopemptoporphyrin, and chlorocruoroporphyrin (Spirographis porphyrin)
- 1 January 1974
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- p. 480-490
- https://doi.org/10.1039/p19740000480
Abstract
Pemptoporphyrin (4-vinyldeuteroporphyrin-IX dimethyl ester) and its 2-vinyl isomer have been synthesised by application of the b-oxobilane and a-oxobilane routes, respectively, thus providing a definitive proof of structure for the natural material. The vinyl groups in each case were introduced through transformation of acetoxyethyl side-chains. Formylation of one of the intermediates (4-chloroethyldeuteroporphyrin), followed by base-catalysed elimination of hydrogen chloride, afforded the dimethyl ester of chlorocruoroporphyrin (2-formyl-4-vinyldeuteroporphyrin-IX).Keywords
This publication has 0 references indexed in Scilit: