Surgical treatment of punctal-canalicular fibrosis from 5-fluorouracil therapy
- 15 October 1985
- Vol. 56 (8) , 2148-2149
- https://doi.org/10.1002/1097-0142(19851015)56:8<2148::aid-cncr2820560845>3.0.co;2-r
Abstract
5-Fluorouracil (5-FU) has been reported to cause punctal-canalicular fibrosis with resultant severe epiphora. It is reported that the epiphora will often resolve when treatment ceases or is decreased. However, this report describes a case of punctal-canalicular fibrosis so severe that bilateral conjunctivodacryocystorhinostomies were necessary. This has not been previously reported to the best of the authors' knowledge. It is recommended that ophthalmic consultation be obtained for patients in whom long-term 5-FU therapy is anticipated or who develop tearing while on therapy. Cancer 56: 2148-2149, 1985.This publication has 6 references indexed in Scilit:
- Ocular Toxicity of Antineoplastic AgentsOphthalmology, 1983
- Punctal-Canalicular Stenosis Related to Systemic Fluorouracil TherapyArchives of Ophthalmology (1950), 1981
- Ocular Side Effects with 5‐FluorouracilAustralian and New Zealand Journal of Medicine, 1979
- Tear-Duct Fibrosis (Dacryostenosis) Due to 5-FluorouracilAnnals of Internal Medicine, 1978
- Excessive Lacrimation From Fluorouracil TreatmentPublished by American Medical Association (AMA) ,1973