Bryostatin-1: A Novel PKC Inhibitor in Clinical Development
- 1 January 2003
- journal article
- review article
- Published by Taylor & Francis in Cancer Investigation
- Vol. 21 (6) , 924-936
- https://doi.org/10.1081/cnv-120025095
Abstract
Modulation of PKC represents a novel approach to cancer therapy. Bryostatin-1 is a macrocyclic lactone derived from a marine invertebrate that binds to the regulatory domain of protein kinase C. Sh...Keywords
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