Synthesis of α-Methylenecarbonyl Compounds: An Unexpected Product from the Mannich Reaction On 2-Carbomethoxycyclohexanone
- 1 January 1973
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 3 (2) , 129-133
- https://doi.org/10.1080/00397917308062021
Abstract
During a study of a general synthesis of α-methylenecarbonyl compounds,1 we investigated the Mannich reaction of 2-carbomethoxycyclohexanone with formaldehyde and various secondary amines. The unexpected formation of 6-methylene-2-carbomethoxycyclohexanone, existing mainly in the enol form, as the only isolable product is the subject of this report.Keywords
This publication has 1 reference indexed in Scilit:
- A new synthesis of α-methylene-γ-butyrolactonesJournal of the Chemical Society D: Chemical Communications, 1970