Mapping catalytically important regions of an enzyme using two-codon insertion mutagenesis: a case study correlating β-lactamase mutants with the three-dimensional structure

This publication has 32 references indexed in Scilit:

• Mutants generated by the insertion of random oligonucleotides into the active site of the .beta.-lactamase gene
  Biochemistry, 1989
• Nucleotide sequence of the gene encoding the Streptomyces albus G beta-lactamase precursor
  European Journal of Biochemistry, 1987
• A genetic system for isolation and characterization of TaqI restriction endonuclease mutants
  Gene, 1987
• Yeast killer toxin: Site-directed mutations implicate the precursor protein as the immunity component
  Cell, 1986
• Potential Metal-Binding Domains in Nucleic Acid Binding Proteins
  Science, 1986
• A temperature-sensitive mutation constructed by “linker insertion” mutagenesis
  Molecular Genetics and Genomics, 1985
• Single-stranded hexameric linkers: a system for in-phase insertion mutagenesis and protein engineering
  Gene, 1985
• One and two codon insertion mutants of bacteriophage f1
  Molecular Genetics and Genomics, 1981
• .beta.-Lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin
  Biochemistry, 1980
• Structural invariants in protein folding
  Nature, 1975