INITIATION OF HUMAN PARTURITION .8. METABOLISM OF PROGESTERONE BY FETAL MEMBRANES OF EARLY AND LATE HUMAN GESTATION

1 January 1977

journal article
research article

Vol. 50 (1) , 45-48

Abstract

A decreased rate of progesterone metabolism was detected in human fetal membranes several weeks preceding normal parturition at term. A 10- to 20-fold decrease in 20.alpha.-hydroxysteroid oxidoreductase activity and a 2- to 6-fold decrease in 5.alpha.-reductase activity were observed in human amnion and chorion laeve after 33 wk gestation.

Keywords

BIOLOGY
CLINICAL RESEARCH
EMBRYO
ENDOCRINE SYSTEM
FETAL MEMBRANES
FETUS
HORMONES
IN VITRO
PHYSIOLOGY
PREGNANCY
PROGESTATIONAL HORMONES
PROGESTERONE--ANALYSIS
REPRODUCTION
RESEARCH METHODOLOGY

This publication has 3 references indexed in Scilit:

Initiation of human parturition
American Journal of Obstetrics and Gynecology, 1976
Thromboxanes: Selective Biosynthesis and Distinct Biological Properties
Science, 1976
INITIATION OF HUMAN PARTURITION .5. PROGESTERONE BINDING SUBSTANCE IN FETAL MEMBRANES
1976