Identification of Human DNA in Complex Biological Samples Using the Alu Polymerase Chain Reaction
- 1 July 1993
- journal article
- Published by ASTM International in Journal of Forensic Sciences
- Vol. 38 (4) , 961-967
- https://doi.org/10.1520/jfs13495j
Abstract
Alu-Polymerase chain reaction (PCR) was used to amplify human DNA from complex mixed sources of DNA. Amplification of human DNA sequences by Alu-PCR could be accomplished in samples containing low concentrations of template in the presence of excess heterologous DNA sequences. Thus, sensitivity and specificity are maintained in complex DNA mixtures allowing positive identification of the presence of human DNA sequences by this technique.Keywords
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