Agarose encapsulation of islets of Langerhans: reduced toxicityin vitro
- 1 January 1987
- journal article
- research article
- Published by Taylor & Francis in Journal of Microencapsulation
- Vol. 4 (3) , 239-242
- https://doi.org/10.3109/02652048709021817
Abstract
The physical and chemical properties of agarose have been exploited for encapsulation of islets of Langerhans. Formation of microcapsules by extrusion of a hydrophilic polymer (agarose) into a hydrophobic solution created an interface to which an immunoprotective membrane could be polymerized. The substances and procedure used were devoid of cellular toxicity. Islet function in vitro was found to be normal.This publication has 4 references indexed in Scilit:
- Optimization of microencapsulation parameters: Semipermeable microcapsules as a bioartificial pancreasBiotechnology & Bioengineering, 1985
- Preparation of microcapsules with possible pharmaceutical useEndeavour, 1985
- Perifusion of Pancreas Fragments: A System for the Study of Dynamic Aspects of Insulin SecretionDiabetes, 1974
- Method for the Isolation of Intact Islets of Langerhans from the Rat PancreasDiabetes, 1967